Bicarbonate or base excess in early obesity hypoventilation syndrome: a methodologic viewpoint.
نویسنده
چکیده
In a recent issue of CHEST (February 2015), Manuel et al 1 reported an original study on obese subjects suggesting that a raised bicarbonate concentration ([HCO 3 2 ]), without awake hypercapnia, could allow the early detection of obesity hypoventilation syndrome (OHS). Since bicarbonate was announced as a potential discriminant biomarker, methodologic issues about its determination should be considered.
منابع مشابه
Defining obesity hypoventilation syndrome.
The definition of obesity hypoventilation syndrome (OHS) proposed by Hart et al raises two questions that we have tried to answer briefly in this letter. First, previous definitions of OHS included obstructive sleep apnoea (OSA); Hart et al have excluded it. Why? OSA is present in most patients with OHS and is partly responsible for the hypercapnia. We believe that it is useful to include it in...
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عنوان ژورنال:
- Chest
دوره 147 6 شماره
صفحات -
تاریخ انتشار 2015